GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THYM | cis | rs2239557 | 1 | rs7153160 | chr14:74509377 | LIN52 | chr14:74551656-74667117:+ | 0.37 | 6.78 | 9.95E-10 | Common traits (Other) |
| THYM | cis | rs2239557 | 1 | rs7153587 | chr14:74509660 | LIN52 | chr14:74551656-74667117:+ | 0.37 | 6.78 | 9.95E-10 | Common traits (Other) |
| THYM | cis | rs2143950 | 1 | rs7154306 | chr14:35540499 | KIAA0391 | chr14:35591776-35786673:+ | 0.32 | 4.16 | 6.96E-5 | Atopic dermatitis |
| THYM | cis | rs2143950 | 1 | rs7154306 | chr14:35540499 | PPP2R3C | chr14:35554679-35591679:- | 0.27 | 5.01 | 2.56E-6 | Atopic dermatitis |
| THYM | cis | rs2143950 | 1 | rs7156322 | chr14:35544330 | KIAA0391 | chr14:35591776-35786673:+ | 0.33 | 4.32 | 3.86E-5 | Atopic dermatitis |
| THYM | cis | rs2143950 | 1 | rs7156322 | chr14:35544330 | PPP2R3C | chr14:35554679-35591679:- | 0.27 | 5.01 | 2.52E-6 | Atopic dermatitis |
| THYM | cis | rs2239557 | 1 | rs7157566 | chr14:74649129 | LIN52 | chr14:74551656-74667117:+ | -0.38 | -6.85 | 7.26E-10 | Common traits (Other) |
| THYM | cis | rs2120019 | 1 | rs7162900 | chr15:75368017 | PPCDC | chr15:75315927-75343066:+ | 0.26 | 4.77 | 6.63E-6 | Blood trace element (Zn levels) |
| THYM | cis | rs2120019 | 1 | rs7167285 | chr15:75368769 | PPCDC | chr15:75315927-75343066:+ | 0.26 | 4.74 | 7.37E-6 | Blood trace element (Zn levels) |
| THYM | cis | rs2120019 | 1 | rs7168680 | chr15:75369212 | PPCDC | chr15:75315927-75343066:+ | 0.26 | 4.7 | 8.93E-6 | Blood trace element (Zn levels) |
| THYM | cis | rs7170930 | 1 | rs7170930 | chr15:66580853 | TIPIN | chr15:66629008-66649054:- | -0.6 | -4.58 | 1.4E-5 | Response to cytadine analogues (cytosine arabinoside) |
| THYM | cis | rs2120019 | 1 | rs7175720 | chr15:75348962 | PPCDC | chr15:75315927-75343066:+ | -0.26 | -4.57 | 1.48E-5 | Blood trace element (Zn levels) |
| THYM | cis | rs4888262 | 1 | rs7191665 | chr16:74688948 | RFWD3 | chr16:74655298-74700779:- | -0.21 | -4.51 | 1.84E-5 | Testicular germ cell tumor |
| THYM | cis | rs8050907 | 1 | rs7195763 | chr16:4649300 | NMRAL1 | chr16:4511696-4526307:- | -0.42 | -4.94 | 3.3E-6 | Obesity-related traits |
| THYM | cis | rs8050907 | 1 | rs7201176 | chr16:4626881 | NMRAL1 | chr16:4511696-4526307:- | -0.48 | -5.52 | 2.96E-7 | Obesity-related traits |